T80UpcomingCategory · further specificity required

Complications following infusion, transfusion and therapeutic injection

Code-level instructions

A — initial encounter

D — subsequent encounter

S — sequela

Chapters 19 · Inherited instructions

Use additional code

code to identify any retained foreign body, if applicable (Z18.-)

T80-T88 · Inherited instructions

Use additional code

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

Excludes 2 · 30

T80

Excludes 2

bone marrow transplant rejection (T86.01)
febrile nonhemolytic transfusion reaction (R50.84)
fluid overload due to transfusion (E87.71)
posttransfusion purpura (D69.51)
transfusion associated circulatory overload (TACO) (E87.71)
transfusion (red blood cell) associated hemochromatosis (E83.111)
transfusion related acute lung injury (TRALI) (J95.84)

Chapters 19 · Injury, poisoning and certain other consequences of external causes (S00-T88)

Excludes 2

birth trauma (P10-P15)
obstetric trauma (O70-O71)

T80-T88 · Complications of surgical and medical care, not elsewhere classified (T80-T88)

Excludes 2

any encounters with medical care for postprocedural conditions in which no complications are present, such as:
artificial opening status (Z93.-)
closure of external stoma (Z43.-)
fitting and adjustment of external prosthetic device (Z44.-)
burns and corrosions from local applications and irradiation (T20-T32)
complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
mechanical complication of respirator [ventilator] (J95.850)
poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
postprocedural fever (R50.82)
specified complications classified elsewhere, such as:
cerebrospinal fluid leak from spinal puncture (G97.0)
colostomy malfunction (K94.0-)
disorders of fluid and electrolyte imbalance (E86-E87)
functional disturbances following cardiac surgery (I97.0-I97.1)
intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
ostomy complications (J95.0-, K94.-, N99.5-)
postgastric surgery syndromes (K91.1)
postlaminectomy syndrome NEC (M96.1)
postmastectomy lymphedema syndrome (I97.2)
postsurgical blind-loop syndrome (K91.2)
ventilator associated pneumonia (J95.851)

More specific codes

T80.0Air embolism following infusion, transfusion and therapeutic injection T80.1Vascular complications following infusion, transfusion and therapeutic injection T80.2Infections following infusion, transfusion and therapeutic injection T80.3ABO incompatibility reaction due to transfusion of blood or blood products T80.4Rh incompatibility reaction due to transfusion of blood or blood products T80.5Anaphylactic reaction due to serum T80.6Other serum reactions T80.8Other complications following infusion, transfusion and therapeutic injection T80.9Unspecified complication following infusion, transfusion and therapeutic injection T80.ANon-ABO incompatibility reaction due to transfusion of blood or blood products

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

First observed · 2015-10-01

Code history

Latest recorded change · FY2025 · 04-01

ChangedUnchanged

FY2025 · 04-01

Effective from 2025-04-01

Inherited rules changed

Complications following infusion, transfusion and therapeutic injection

Category — select a more specific code

CDC/NCHS · FY2025 · 04-01

All editions (19)

All editions	Effective from	Code history
FY2016	2015-10-01	First observed
FY2017	2016-10-01	Inherited rules changed
FY2018	2017-10-01	No tabular change
FY2019	2018-10-01	No tabular change
FY2020	2019-10-01	No tabular change
FY2020 · April	2020-04-01	No tabular change
FY2021	2020-10-01	No tabular change
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	Inherited rules changed
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Includes

complications following perfusion

Excludes 2

bone marrow transplant rejection (T86.01)
febrile nonhemolytic transfusion reaction (R50.84)
fluid overload due to transfusion (E87.71)
posttransfusion purpura (D69.51)
transfusion associated circulatory overload (TACO) (E87.71)
transfusion (red blood cell) associated hemochromatosis (E83.111)
transfusion related acute lung injury (TRALI) (J95.84)

Seventh character

The appropriate 7th character is to be added to each code from category T80

A — initial encounter

D — subsequent encounter

S — sequela

Inherited instructions

Chapters 19 · Injury, poisoning and certain other consequences of external causes (S00-T88)

Excludes 2

birth trauma (P10-P15)
obstetric trauma (O70-O71)

Use additional code

code to identify any retained foreign body, if applicable (Z18.-)

Note

Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

T80-T88 · Complications of surgical and medical care, not elsewhere classified (T80-T88)

Excludes 2

any encounters with medical care for postprocedural conditions in which no complications are present, such as:
artificial opening status (Z93.-)
closure of external stoma (Z43.-)
fitting and adjustment of external prosthetic device (Z44.-)
burns and corrosions from local applications and irradiation (T20-T32)
complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
mechanical complication of respirator [ventilator] (J95.850)
poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
postprocedural fever (R50.82)
specified complications classified elsewhere, such as:
cerebrospinal fluid leak from spinal puncture (G97.0)
colostomy malfunction (K94.0-)
disorders of fluid and electrolyte imbalance (E86-E87)
functional disturbances following cardiac surgery (I97.0-I97.1)
intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
ostomy complications (J95.0-, K94.-, N99.5-)
postgastric surgery syndromes (K91.1)
postlaminectomy syndrome NEC (M96.1)
postmastectomy lymphedema syndrome (I97.2)
postsurgical blind-loop syndrome (K91.2)
ventilator associated pneumonia (J95.851)

Use additional code

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
code(s) to identify the specified condition resulting from the complication
code to identify devices involved and details of circumstances (Y62-Y82)

More specific codes

Related codes

Official titles and instructions are preserved in their source language. Official sources ↗

References from other codes (8)

P00.89 · Newborn affected by other maternal conditions

Inclusion terms · Newborn affected by conditions classifiable to T80-T88

T45.8 · Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents

Excludes 2 · transfusion reactions (T80.-)

T78 · Adverse effects, not elsewhere classified

Excludes 2 · complications of surgical and medical care NEC (T80-T88)

T79 · Certain early complications of trauma, not elsewhere classified

Excludes 2 · complications occurring during or following medical procedures (T80-T88)

T79 · Certain early complications of trauma, not elsewhere classified

Excludes 2 · complications of surgical and medical care NEC (T80-T88)

T81 · Complications of procedures, not elsewhere classified

Excludes 2 · complications following infusion, transfusion and therapeutic injection (T80.-)

T88 · Other complications of surgical and medical care, not elsewhere classified

Excludes 2 · complication following infusion, transfusion and therapeutic injection (T80.-)

T88.7 · Unspecified adverse effect of drug or medicament

Excludes 1 · specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)