Effective from
- Code-level rules changed
Poisoning by immune checkpoint inhibitors and immunostimulant drugs, accidental (unintentional)
Category — select a more specific code
CDC/NCHS · FY2027code to identify any retained foreign body, if applicable (Z18.-)
toxic reaction to local anesthesia in pregnancy (O29.3-)
A — initial encounter
D — subsequent encounter
S — sequela
poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drug (T45.1)
For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.
Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.
Official coding guidelines → · CMS ↗First observed · 2024-10-01
Latest recorded change · FY2027
Effective from
Poisoning by immune checkpoint inhibitors and immunostimulant drugs, accidental (unintentional)
Category — select a more specific code
CDC/NCHS · FY2027| All editions | Effective from | Code history |
|---|---|---|
| FY2025 | 2024-10-01 | Added |
| FY2025 · 04-01 | 2025-04-01 | Inherited rules changed |
| FY2026 | 2025-10-01 | No tabular change |
| FY2026 · April | 2026-04-01 | No tabular change |
| FY2027 | 2026-10-01 | Code-level rules changed |
Poisoning by immune checkpoint inhibitors and immunosuppressive drugs NOS
code to identify any retained foreign body, if applicable (Z18.-)
toxic reaction to local anesthesia in pregnancy (O29.3-)
The appropriate 7th character is to be added to each code from category T45
A — initial encounter
D — subsequent encounter
S — sequela
poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drug (T45.1)
T45.AX1APoisoning by immune checkpoint inhibitors and immunostimulant drugs, accidental (unintentional), initial encounterBillable / specificT45.AX1DPoisoning by immune checkpoint inhibitors and immunostimulant drugs, accidental (unintentional), subsequent encounterBillable / specificT45.AX1SPoisoning by immune checkpoint inhibitors and immunostimulant drugs, accidental (unintentional), sequelaBillable / specificOther entries in the same category; these are not automatic substitutes.
| Code | Description | Category · further specificity required |
|---|---|---|
| T45.AX2 | Poisoning by immune checkpoint inhibitors and immunostimulant drugs, intentional self-harm | Category · further specificity required |
| T45.AX3 | Poisoning by immune checkpoint inhibitors and immunostimulant drugs, assault | Category · further specificity required |
| T45.AX4 | Poisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined | Category · further specificity required |
| T45.AX5 | Adverse effect of immune checkpoint inhibitors and immunostimulant drugs | Category · further specificity required |
| T45.AX6 | Underdosing of immune checkpoint inhibitors and immunostimulant drugs | Category · further specificity required |
Official titles and instructions are preserved in their source language. Official sources ↗