Z92.85UpcomingCategory · further specificity required

Personal history of cellular therapy

Z77-Z99 · Inherited instructions

Code also

any follow-up examination (Z08-Z09)

Excludes 2 · 2

Z92.85

Excludes 2

personal history of immune checkpoint inhibitor therapy (Z92.26)

Z92 · Personal history of medical treatment

Excludes 2

postprocedural states (Z98.-)

More specific codes

Z92.850Personal history of Chimeric Antigen Receptor T-cell therapy Z92.858Personal history of other cellular therapy Z92.859Personal history of cellular therapy, unspecified

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

First observed · 2021-10-01

Code history

Latest recorded change · FY2025

ChangedUnchanged

FY2025

Effective from 2024-10-01

Code-level rules changed

Personal history of cellular therapy

Category — select a more specific code

CDC/NCHS · FY2025

All editions (11)

All editions	Effective from	Code history
FY2022	2021-10-01	Added
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	Code-level rules changed
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Excludes 2

personal history of immune checkpoint inhibitor therapy (Z92.26)

Inherited instructions

Chapters 21 · Factors influencing health status and contact with health services (Z00-Z99)

Note

Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
(a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
(b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Z77-Z99 · Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99)

Code also

any follow-up examination (Z08-Z09)

Z92 · Personal history of medical treatment

Excludes 2

postprocedural states (Z98.-)

More specific codes

Z92.850Personal history of Chimeric Antigen Receptor T-cell therapyBillable / specific Z92.858Personal history of other cellular therapyBillable / specific Z92.859Personal history of cellular therapy, unspecifiedBillable / specific

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
Z92.81	Personal history of extracorporeal membrane oxygenation (ECMO)	Billable / specific
Z92.82	Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility	Billable / specific
Z92.83	Personal history of failed moderate sedation	Billable / specific
Z92.84	Personal history of unintended awareness under general anesthesia	Billable / specific
Z92.86	Personal history of gene therapy	Billable / specific
Z92.89	Personal history of other medical treatment	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗

Z92.85UpcomingCategory · further specificity required

Personal history of cellular therapy

Z77-Z99 · Inherited instructions

Code also

any follow-up examination (Z08-Z09)

Excludes 2 · 2

Z92.85

Excludes 2

personal history of immune checkpoint inhibitor therapy (Z92.26)

Z92 · Personal history of medical treatment

Excludes 2

postprocedural states (Z98.-)

More specific codes

Z92.850Personal history of Chimeric Antigen Receptor T-cell therapy Z92.858Personal history of other cellular therapy Z92.859Personal history of cellular therapy, unspecified

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

First observed · 2021-10-01

Code history

Latest recorded change · FY2025

ChangedUnchanged

FY2025

Effective from 2024-10-01

Code-level rules changed

Personal history of cellular therapy

Category — select a more specific code

CDC/NCHS · FY2025

All editions (11)

All editions	Effective from	Code history
FY2022	2021-10-01	Added
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	Code-level rules changed
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Excludes 2

personal history of immune checkpoint inhibitor therapy (Z92.26)

Inherited instructions

Chapters 21 · Factors influencing health status and contact with health services (Z00-Z99)

Note

Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
(a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
(b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Z77-Z99 · Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99)

Code also

any follow-up examination (Z08-Z09)

Z92 · Personal history of medical treatment

Excludes 2

postprocedural states (Z98.-)

More specific codes

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
Z92.81	Personal history of extracorporeal membrane oxygenation (ECMO)	Billable / specific
Z92.82	Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility	Billable / specific
Z92.83	Personal history of failed moderate sedation	Billable / specific
Z92.84	Personal history of unintended awareness under general anesthesia	Billable / specific
Z92.86	Personal history of gene therapy	Billable / specific
Z92.89	Personal history of other medical treatment	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗