Effective from
- Code-level rules changed
Long term (current) use of opiate analgesic
Billable diagnosis code
CDC/NCHS · FY2026 · Aprilany therapeutic drug level monitoring (Z51.81)
Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.
For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.
Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.
Official coding guidelines → · CMS ↗First observed · 2015-10-01
Latest recorded change · FY2026 · April
Effective from
Long term (current) use of opiate analgesic
Billable diagnosis code
CDC/NCHS · FY2026 · April| All editions | Effective from | Code history |
|---|---|---|
| FY2016 | 2015-10-01 | First observed |
| FY2017 | 2016-10-01 | Code-level rules changed · Inherited rules changed |
| FY2018 | 2017-10-01 | No tabular change |
| FY2019 | 2018-10-01 | No tabular change |
| FY2020 | 2019-10-01 | No tabular change |
| FY2020 · April | 2020-04-01 | No tabular change |
| FY2021 | 2020-10-01 | Inherited rules changed |
| FY2021 · 01-01 | 2021-01-01 | No tabular change |
| FY2022 | 2021-10-01 | No tabular change |
| FY2022 · 04-01 | 2022-04-01 | No tabular change |
| FY2023 | 2022-10-01 | No tabular change |
| FY2023 · 04-01 | 2023-04-01 | No tabular change |
| FY2024 | 2023-10-01 | No tabular change |
| FY2024 · 04-01 | 2024-04-01 | No tabular change |
| FY2025 | 2024-10-01 | No tabular change |
| FY2025 · 04-01 | 2025-04-01 | No tabular change |
| FY2026 | 2025-10-01 | No tabular change |
| FY2026 · April | 2026-04-01 | Code-level rules changed |
| FY2027 | 2026-10-01 | No tabular change |
Historical mapping only; not an automatic code substitution.
Long term (current) use of methadone for pain management
long term (current) drug use for prophylactic purposes
any therapeutic drug level monitoring (Z51.81)
Other entries in the same category; these are not automatic substitutes.
| Code | Description | Category · further specificity required |
|---|---|---|
| Z79.890 | Hormone replacement therapy | Billable / specific |
| Z79.899 | Other long term (current) drug therapy | Billable / specific |
Official titles and instructions are preserved in their source language. Official sources ↗