Code edition

UpcomingOct 1, 2026 – Sep 30, 2027

R11.16UpcomingBillable / specific

Cannabis hyperemesis syndrome

Code-level instructions

Code also

cannabis abuse (F12.1-)
cannabis dependence (F12.2-)
cannabis use, unspecified (F12.92-, F12.93, F12.95-, F12.98-, F12.99)
manifestations, such as:
dehydration (E86.0)
electrolyte imbalance (E87.8)

R11 · Inherited instructions

Excludes 1

cyclical vomiting associated with migraine (G43.A-)
excessive vomiting in pregnancy (O21.-)
hematemesis (K92.0)
neonatal hematemesis (P54.0)
newborn vomiting (P92.0-)
psychogenic vomiting (F50.89)
vomiting associated with bulimia nervosa (F50.2-)
vomiting following gastrointestinal surgery (K91.0)

Excludes 2 · 13

Chapters 18 · Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

Excludes 2

abnormal findings on antenatal screening of mother (O28.-)
certain conditions originating in the perinatal period (P04-P96)
signs and symptoms classified in the body system chapters
signs and symptoms of breast (N63, N64.5)

R10-R19 · Symptoms and signs involving the digestive system and abdomen (R10-R19)

Excludes 2

congenital or infantile pylorospasm (Q40.0)
gastrointestinal hemorrhage (K92.0-K92.2)
intestinal obstruction (K56.-)
newborn gastrointestinal hemorrhage (P54.0-P54.3)
newborn intestinal obstruction (P76.-)
pylorospasm (K31.3)
signs and symptoms involving the urinary system (R30-R39)
symptoms referable to female genital organs (N94.-)
symptoms referable to male genital organs (N48-N50)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

Check Medicare coverage ↗

First observed · 2025-10-01

Code history

Latest recorded change · FY2027

ChangedUnchanged

FY2027UpcomingSelected edition

Effective from 2026-10-01

Code-level rules changed

Cannabis hyperemesis syndrome

Billable diagnosis code

CDC/NCHS · FY2027

All editions (3)

All editions	Effective from	Code history
FY2026	2025-10-01	Added
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	Code-level rules changed

Code-level instructions

Inclusion terms

Cannabinoid hyperemesis syndrome

Code also

cannabis abuse (F12.1-)
cannabis dependence (F12.2-)
cannabis use, unspecified (F12.92-, F12.93, F12.95-, F12.98-, F12.99)
manifestations, such as:
dehydration (E86.0)
electrolyte imbalance (E87.8)

Inherited instructions

Chapters 18 · Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

Excludes 2

abnormal findings on antenatal screening of mother (O28.-)
certain conditions originating in the perinatal period (P04-P96)
signs and symptoms classified in the body system chapters
signs and symptoms of breast (N63, N64.5)

Note

This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
The conditions and signs or symptoms included in categories R00-R94 consist of:
(a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
(b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
(c) provisional diagnosis in a patient who failed to return for further investigation or care;
(d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
(e) cases in which a more precise diagnosis was not available for any other reason;
(f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

R10-R19 · Symptoms and signs involving the digestive system and abdomen (R10-R19)

Excludes 2

congenital or infantile pylorospasm (Q40.0)
gastrointestinal hemorrhage (K92.0-K92.2)
intestinal obstruction (K56.-)
newborn gastrointestinal hemorrhage (P54.0-P54.3)
newborn intestinal obstruction (P76.-)
pylorospasm (K31.3)
signs and symptoms involving the urinary system (R30-R39)
symptoms referable to female genital organs (N94.-)
symptoms referable to male genital organs (N48-N50)

R11 · Nausea and vomiting

Excludes 1

cyclical vomiting associated with migraine (G43.A-)
excessive vomiting in pregnancy (O21.-)
hematemesis (K92.0)
neonatal hematemesis (P54.0)
newborn vomiting (P92.0-)
psychogenic vomiting (F50.89)
vomiting associated with bulimia nervosa (F50.2-)
vomiting following gastrointestinal surgery (K91.0)

Official index references (2)

Syndrome (2)

Syndrome › cannabinoid hyperemesisDisease index
Syndrome › cannabis hyperemesisDisease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2025-10-01

Previous assignment: R11.10

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
R11.10	Vomiting, unspecified	Billable / specific
R11.11	Vomiting without nausea	Billable / specific
R11.12	Projectile vomiting	Billable / specific
R11.13	Vomiting of fecal matter	Billable / specific
R11.14	Bilious vomiting	Billable / specific
R11.15	Cyclical vomiting syndrome unrelated to migraine	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗

R11.16UpcomingBillable / specific

Cannabis hyperemesis syndrome

Code-level instructions

Code also

cannabis abuse (F12.1-)
cannabis dependence (F12.2-)
cannabis use, unspecified (F12.92-, F12.93, F12.95-, F12.98-, F12.99)
manifestations, such as:
dehydration (E86.0)
electrolyte imbalance (E87.8)

R11 · Inherited instructions

Excludes 1

cyclical vomiting associated with migraine (G43.A-)
excessive vomiting in pregnancy (O21.-)
hematemesis (K92.0)
neonatal hematemesis (P54.0)
newborn vomiting (P92.0-)
psychogenic vomiting (F50.89)
vomiting associated with bulimia nervosa (F50.2-)
vomiting following gastrointestinal surgery (K91.0)

Excludes 2 · 13

Chapters 18 · Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

Excludes 2

abnormal findings on antenatal screening of mother (O28.-)
certain conditions originating in the perinatal period (P04-P96)
signs and symptoms classified in the body system chapters
signs and symptoms of breast (N63, N64.5)

R10-R19 · Symptoms and signs involving the digestive system and abdomen (R10-R19)

Excludes 2

congenital or infantile pylorospasm (Q40.0)
gastrointestinal hemorrhage (K92.0-K92.2)
intestinal obstruction (K56.-)
newborn gastrointestinal hemorrhage (P54.0-P54.3)
newborn intestinal obstruction (P76.-)
pylorospasm (K31.3)
signs and symptoms involving the urinary system (R30-R39)
symptoms referable to female genital organs (N94.-)
symptoms referable to male genital organs (N48-N50)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

Check Medicare coverage ↗

First observed · 2025-10-01

Code history

Latest recorded change · FY2027

ChangedUnchanged

FY2027UpcomingSelected edition

Effective from 2026-10-01

Code-level rules changed

Cannabis hyperemesis syndrome

Billable diagnosis code

CDC/NCHS · FY2027

All editions (3)

All editions	Effective from	Code history
FY2026	2025-10-01	Added
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	Code-level rules changed

Code-level instructions

Inclusion terms

Cannabinoid hyperemesis syndrome

Code also

cannabis abuse (F12.1-)
cannabis dependence (F12.2-)
cannabis use, unspecified (F12.92-, F12.93, F12.95-, F12.98-, F12.99)
manifestations, such as:
dehydration (E86.0)
electrolyte imbalance (E87.8)

Inherited instructions

Chapters 18 · Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

Excludes 2

abnormal findings on antenatal screening of mother (O28.-)
certain conditions originating in the perinatal period (P04-P96)
signs and symptoms classified in the body system chapters
signs and symptoms of breast (N63, N64.5)

Note

This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
The conditions and signs or symptoms included in categories R00-R94 consist of:
(a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
(b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
(c) provisional diagnosis in a patient who failed to return for further investigation or care;
(d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
(e) cases in which a more precise diagnosis was not available for any other reason;
(f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

R10-R19 · Symptoms and signs involving the digestive system and abdomen (R10-R19)

Excludes 2

congenital or infantile pylorospasm (Q40.0)
gastrointestinal hemorrhage (K92.0-K92.2)
intestinal obstruction (K56.-)
newborn gastrointestinal hemorrhage (P54.0-P54.3)
newborn intestinal obstruction (P76.-)
pylorospasm (K31.3)
signs and symptoms involving the urinary system (R30-R39)
symptoms referable to female genital organs (N94.-)
symptoms referable to male genital organs (N48-N50)

R11 · Nausea and vomiting

Excludes 1

cyclical vomiting associated with migraine (G43.A-)
excessive vomiting in pregnancy (O21.-)
hematemesis (K92.0)
neonatal hematemesis (P54.0)
newborn vomiting (P92.0-)
psychogenic vomiting (F50.89)
vomiting associated with bulimia nervosa (F50.2-)
vomiting following gastrointestinal surgery (K91.0)

Official index references (2)

Syndrome (2)

Syndrome › cannabinoid hyperemesisDisease index
Syndrome › cannabis hyperemesisDisease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2025-10-01

Previous assignment: R11.10

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
R11.10	Vomiting, unspecified	Billable / specific
R11.11	Vomiting without nausea	Billable / specific
R11.12	Projectile vomiting	Billable / specific
R11.13	Vomiting of fecal matter	Billable / specific
R11.14	Bilious vomiting	Billable / specific
R11.15	Cyclical vomiting syndrome unrelated to migraine	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗