M31.11UpcomingBillable / specific

Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

Code-level instructions

Code first

if applicable:
complications of bone marrow transplant (T86.0-)
complications of stem cell transplant (T86.5)

Use additional code

code to identify specific organ dysfunction, such as:
acute kidney failure (N17.-)
acute respiratory distress syndrome (J80)
capillary leak syndrome (I78.8)
diffuse alveolar hemorrhage (R04.89)
encephalopathy (metabolic) (septic) (G93.41)
fluid overload, unspecified (E87.70)
graft versus host disease (D89.81-)
hemolytic uremic syndrome (D59.3-)
hepatic failure (K72.-)
hepatic veno-occlusive disease (K76.5)
idiopathic interstitial pneumonia (J84.11-)
sinusoidal obstruction syndrome (K76.5)

M30-M36 · Inherited instructions

Excludes 1

autoimmune disease, single organ or single cell-type -code to relevant condition category

Excludes 2 · 10

Chapters 13 · Diseases of the musculoskeletal system and connective tissue (M00-M99)

Excludes 2

arthropathic psoriasis (L40.5-)
certain conditions originating in the perinatal period (P04-P96)
certain infectious and parasitic diseases (A00-B99)
compartment syndrome (traumatic) (T79.A-)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

Check Medicare coverage ↗

First observed · 2021-10-01

Code history

Latest recorded change · FY2023

ChangedUnchanged

FY2023

Effective from 2022-10-01

Code-level rules changed

Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

Billable diagnosis code

CDC/NCHS · FY2023

All editions (11)

All editions	Effective from	Code history
FY2022	2021-10-01	Added
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	Code-level rules changed
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Inclusion terms

Transplant-associated thrombotic microangiopathy [TA-TMA]

Code first

if applicable:
complications of bone marrow transplant (T86.0-)
complications of stem cell transplant (T86.5)

Use additional code

code to identify specific organ dysfunction, such as:
acute kidney failure (N17.-)
acute respiratory distress syndrome (J80)
capillary leak syndrome (I78.8)
diffuse alveolar hemorrhage (R04.89)
encephalopathy (metabolic) (septic) (G93.41)
fluid overload, unspecified (E87.70)
graft versus host disease (D89.81-)
hemolytic uremic syndrome (D59.3-)
hepatic failure (K72.-)
hepatic veno-occlusive disease (K76.5)
idiopathic interstitial pneumonia (J84.11-)
sinusoidal obstruction syndrome (K76.5)

Inherited instructions

Chapters 13 · Diseases of the musculoskeletal system and connective tissue (M00-M99)

Excludes 2

arthropathic psoriasis (L40.5-)
certain conditions originating in the perinatal period (P04-P96)
certain infectious and parasitic diseases (A00-B99)
compartment syndrome (traumatic) (T79.A-)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Note

Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

M30-M36 · Systemic connective tissue disorders (M30-M36)

Includes

autoimmune disease NOS
collagen (vascular) disease NOS
systemic autoimmune disease
systemic collagen (vascular) disease

Excludes 1

autoimmune disease, single organ or single cell-type -code to relevant condition category

Official index references (2)

HSCT-TMA(hematopoietic stem cell transplantation-associated thrombotic microangiopathy) (1)

HSCT-TMA(hematopoietic stem cell transplantation-associated thrombotic microangiopathy)Disease index

Microangiopathy(peripheral) (1)

Microangiopathy(peripheral) › thrombotic › hematopoietic stem cell transplantation-associated [HSCT-TMA]Disease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2021-10-01

Previous assignment: M31.1

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
M31.10	Thrombotic microangiopathy, unspecified	Billable / specific
M31.19	Other thrombotic microangiopathy	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗

Code-level instructions

Code first

if applicable:
complications of bone marrow transplant (T86.0-)
complications of stem cell transplant (T86.5)

Use additional code

code to identify specific organ dysfunction, such as:
acute kidney failure (N17.-)
acute respiratory distress syndrome (J80)
capillary leak syndrome (I78.8)
diffuse alveolar hemorrhage (R04.89)
encephalopathy (metabolic) (septic) (G93.41)
fluid overload, unspecified (E87.70)
graft versus host disease (D89.81-)
hemolytic uremic syndrome (D59.3-)
hepatic failure (K72.-)
hepatic veno-occlusive disease (K76.5)
idiopathic interstitial pneumonia (J84.11-)
sinusoidal obstruction syndrome (K76.5)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

Check Medicare coverage ↗

All editions

Effective from

Code history

FY2022

2021-10-01

Added

FY2022 · 04-01

2022-04-01

No tabular change

FY2023

2022-10-01

Code-level rules changed

FY2023 · 04-01

2023-04-01

No tabular change

FY2024

2023-10-01

No tabular change

FY2024 · 04-01

2024-04-01

No tabular change

FY2025

2024-10-01

No tabular change

FY2025 · 04-01

2025-04-01

No tabular change

FY2026

2025-10-01

No tabular change

FY2026 · April

2026-04-01

No tabular change

FY2027

2026-10-01

No tabular change