K21.00UpcomingBillable / specific

Gastro-esophageal reflux disease with esophagitis, without bleeding

K21 · Inherited instructions

Excludes 1

newborn esophageal reflux (P78.83)

Excludes 2 · 9

Chapters 11 · Diseases of the digestive system (K00-K95)

Excludes 2

certain conditions originating in the perinatal period (P04-P96)
certain infectious and parasitic diseases (A00-B99)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

K20-K31 · Diseases of esophagus, stomach and duodenum (K20-K31)

Excludes 2

hiatus hernia (K44.-)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

Check Medicare coverage ↗

First observed · 2020-10-01

Code history

Latest recorded change · FY2021

ChangedUnchanged

FY2021

Effective from 2020-10-01

Added

Gastro-esophageal reflux disease with esophagitis, without bleeding

Billable diagnosis code

CDC/NCHS · FY2021

All editions (13)

All editions	Effective from	Code history
FY2021	2020-10-01	Added
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Inclusion terms

Reflux esophagitis

Inherited instructions

Chapters 11 · Diseases of the digestive system (K00-K95)

Excludes 2

certain conditions originating in the perinatal period (P04-P96)
certain infectious and parasitic diseases (A00-B99)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

K20-K31 · Diseases of esophagus, stomach and duodenum (K20-K31)

Excludes 2

hiatus hernia (K44.-)

K21 · Gastro-esophageal reflux disease

Excludes 1

newborn esophageal reflux (P78.83)

Official index references (7)

Allergy, allergic(reaction) (to) (1)

Allergy, allergic(reaction) (to) › milk protein › gastroesophageal reflux › with esophagitis(without bleeding)Disease index

Disease, diseased (1)

Disease, diseased › gastroesophageal reflux(GERD) › with esophagitis(without bleeding)Disease index

Esophagitis(acute) (alkaline) (chemical) (chronic) (infectional) (necrotic) (peptic) (postoperative) (without bleeding) (2)

Reflux (2)

Reflux › esophageal › with esophagitis(without bleeding)Disease index
Reflux › gastroesophageal › with esophagitis(without bleeding)Disease index

Ulcer, ulcerated, ulcerating, ulceration, ulcerative (1)

Ulcer, ulcerated, ulcerating, ulceration, ulcerative › esophagus(peptic) › due to › gastrointestinal reflux disease(without bleeding)Disease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2020-10-01

Previous assignment: K21.0

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
K21.01	Gastro-esophageal reflux disease with esophagitis, with bleeding	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗

K21.00UpcomingBillable / specific

Gastro-esophageal reflux disease with esophagitis, without bleeding

K21 · Inherited instructions

Excludes 1

newborn esophageal reflux (P78.83)

Excludes 2 · 9

Chapters 11 · Diseases of the digestive system (K00-K95)

Excludes 2

certain conditions originating in the perinatal period (P04-P96)
certain infectious and parasitic diseases (A00-B99)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

K20-K31 · Diseases of esophagus, stomach and duodenum (K20-K31)

Excludes 2

hiatus hernia (K44.-)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

Check Medicare coverage ↗

First observed · 2020-10-01

Code history

Latest recorded change · FY2021

ChangedUnchanged

FY2021

Effective from 2020-10-01

Added

Gastro-esophageal reflux disease with esophagitis, without bleeding

Billable diagnosis code

CDC/NCHS · FY2021

All editions (13)

All editions	Effective from	Code history
FY2021	2020-10-01	Added
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Inclusion terms

Reflux esophagitis

Inherited instructions

Chapters 11 · Diseases of the digestive system (K00-K95)

Excludes 2

certain conditions originating in the perinatal period (P04-P96)
certain infectious and parasitic diseases (A00-B99)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

K20-K31 · Diseases of esophagus, stomach and duodenum (K20-K31)

Excludes 2

hiatus hernia (K44.-)

K21 · Gastro-esophageal reflux disease

Excludes 1

newborn esophageal reflux (P78.83)

Official index references (7)

Allergy, allergic(reaction) (to) (1)

Allergy, allergic(reaction) (to) › milk protein › gastroesophageal reflux › with esophagitis(without bleeding)Disease index

Disease, diseased (1)

Disease, diseased › gastroesophageal reflux(GERD) › with esophagitis(without bleeding)Disease index

Esophagitis(acute) (alkaline) (chemical) (chronic) (infectional) (necrotic) (peptic) (postoperative) (without bleeding) (2)

Reflux (2)

Reflux › esophageal › with esophagitis(without bleeding)Disease index
Reflux › gastroesophageal › with esophagitis(without bleeding)Disease index

Ulcer, ulcerated, ulcerating, ulceration, ulcerative (1)

Ulcer, ulcerated, ulcerating, ulceration, ulcerative › esophagus(peptic) › due to › gastrointestinal reflux disease(without bleeding)Disease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2020-10-01

Previous assignment: K21.0

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
K21.01	Gastro-esophageal reflux disease with esophagitis, with bleeding	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗