Effective from
- Code-level rules changed
Disorders of plasma-protein metabolism, not elsewhere classified
Category — select a more specific code
CDC/NCHS · FY2025codes for associated conditions
histiocytosis X (chronic) (C96.6)
disorder of lipoprotein metabolism (E78.-)
Ehlers-Danlos syndromes (Q79.6-)
For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.
Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.
Official coding guidelines → · CMS ↗First observed · 2015-10-01
Latest recorded change · FY2025
Effective from
Disorders of plasma-protein metabolism, not elsewhere classified
Category — select a more specific code
CDC/NCHS · FY2025| All editions | Effective from | Code history |
|---|---|---|
| FY2016 | 2015-10-01 | First observed |
| FY2017 | 2016-10-01 | No tabular change |
| FY2018 | 2017-10-01 | No tabular change |
| FY2019 | 2018-10-01 | No tabular change |
| FY2020 | 2019-10-01 | Inherited rules changed |
| FY2020 · April | 2020-04-01 | No tabular change |
| FY2021 | 2020-10-01 | Code-level rules changed · Inherited rules changed |
| FY2021 · 01-01 | 2021-01-01 | No tabular change |
| FY2022 | 2021-10-01 | Inherited rules changed |
| FY2022 · 04-01 | 2022-04-01 | No tabular change |
| FY2023 | 2022-10-01 | No tabular change |
| FY2023 · 04-01 | 2023-04-01 | No tabular change |
| FY2024 | 2023-10-01 | Inherited rules changed |
| FY2024 · 04-01 | 2024-04-01 | No tabular change |
| FY2025 | 2024-10-01 | Code-level rules changed |
| FY2025 · 04-01 | 2025-04-01 | No tabular change |
| FY2026 | 2025-10-01 | No tabular change |
| FY2026 · April | 2026-04-01 | No tabular change |
| FY2027 | 2026-10-01 | No tabular change |
disorder of lipoprotein metabolism (E78.-)
histiocytosis X (chronic) (C96.6)
codes for associated conditions
All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Ehlers-Danlos syndromes (Q79.6-)
Other entries in the same category; these are not automatic substitutes.
| Code | Description | Category · further specificity required |
|---|---|---|
| E88.1 | Lipodystrophy, not elsewhere classified | Category · further specificity required |
| E88.2 | Lipomatosis, not elsewhere classified | Billable / specific |
| E88.3 | Tumor lysis syndrome | Billable / specific |
| E88.4 | Mitochondrial metabolism disorders | Category · further specificity required |
| E88.8 | Other specified metabolic disorders | Category · further specificity required |
| E88.9 | Metabolic disorder, unspecified | Billable / specific |
| E88.A | Wasting disease (syndrome) due to underlying condition | Billable / specific |
Official titles and instructions are preserved in their source language. Official sources ↗
Excludes 1 · disorders of plasma-protein metabolism (E88.0-)