D70UpcomingCategory · further specificity required

Neutropenia

Code-level instructions

Use additional code

code for any associated:
fever (R50.81)

Code also

, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)

Excludes 1

neutropenic splenomegaly (D73.81)
transient neonatal neutropenia (P61.5)

Excludes 2 · 9

Chapters 3 · Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Excludes 2

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

More specific codes

D70.0Congenital agranulocytosis D70.1Agranulocytosis secondary to cancer chemotherapy D70.2Other drug-induced agranulocytosis D70.3Neutropenia due to infection D70.4Cyclic neutropenia D70.8Other neutropenia D70.9Neutropenia, unspecified

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

First observed · 2015-10-01

Code history

Latest recorded change · FY2024

ChangedUnchanged

FY2024

Effective from 2023-10-01

Code-level rules changed

Neutropenia

Category — select a more specific code

CDC/NCHS · FY2024

All editions (19)

All editions	Effective from	Code history
FY2016	2015-10-01	First observed
FY2017	2016-10-01	No tabular change
FY2018	2017-10-01	No tabular change
FY2019	2018-10-01	No tabular change
FY2020	2019-10-01	No tabular change
FY2020 · April	2020-04-01	No tabular change
FY2021	2020-10-01	No tabular change
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	Code-level rules changed
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Includes

agranulocytosis
decreased absolute neurophile count (ANC)

Excludes 1

neutropenic splenomegaly (D73.81)
transient neonatal neutropenia (P61.5)

Use additional code

code for any associated:
fever (R50.81)

Code also

, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)

Inherited instructions

Chapters 3 · Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Excludes 2

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

More specific codes

D70.0Congenital agranulocytosisBillable / specific D70.1Agranulocytosis secondary to cancer chemotherapyBillable / specific D70.2Other drug-induced agranulocytosisBillable / specific D70.3Neutropenia due to infectionBillable / specific D70.4Cyclic neutropeniaBillable / specific D70.8Other neutropeniaBillable / specific D70.9Neutropenia, unspecifiedBillable / specific

Related codes

Official titles and instructions are preserved in their source language. Official sources ↗

References from other codes (5)

D61 · Other aplastic anemias and other bone marrow failure syndromes

Excludes 2 · neutropenia (D70.-)

D72 · Other disorders of white blood cells

Excludes 2 · neutropenia (D70)

D72.81 · Decreased white blood cell count

Excludes 2 · neutropenia (D70)

R50.81 · Fever presenting with conditions classified elsewhere

Code first · neutropenia (D70.-)

sections/R70-R79 · Abnormal findings on examination of blood, without diagnosis (R70-R79)

Excludes 2 · abnormalities of white blood cells classified elsewhere (D70-D72)

D70UpcomingCategory · further specificity required

Neutropenia

Code-level instructions

Use additional code

code for any associated:
fever (R50.81)

Code also

, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)

Excludes 1

neutropenic splenomegaly (D73.81)
transient neonatal neutropenia (P61.5)

Excludes 2 · 9

Chapters 3 · Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Excludes 2

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

More specific codes

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

First observed · 2015-10-01

Code history

Latest recorded change · FY2024

ChangedUnchanged

FY2024

Effective from 2023-10-01

Code-level rules changed

Neutropenia

Category — select a more specific code

CDC/NCHS · FY2024

All editions (19)

All editions	Effective from	Code history
FY2016	2015-10-01	First observed
FY2017	2016-10-01	No tabular change
FY2018	2017-10-01	No tabular change
FY2019	2018-10-01	No tabular change
FY2020	2019-10-01	No tabular change
FY2020 · April	2020-04-01	No tabular change
FY2021	2020-10-01	No tabular change
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	Code-level rules changed
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	No tabular change
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Includes

agranulocytosis
decreased absolute neurophile count (ANC)

Excludes 1

neutropenic splenomegaly (D73.81)
transient neonatal neutropenia (P61.5)

Use additional code

code for any associated:
fever (R50.81)

Code also

, if applicable, mucositis (J34.81, K12.3-, K92.81, N76.81)

Inherited instructions

Chapters 3 · Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Excludes 2

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

More specific codes

Related codes

Official titles and instructions are preserved in their source language. Official sources ↗

References from other codes (5)

D61 · Other aplastic anemias and other bone marrow failure syndromes

Excludes 2 · neutropenia (D70.-)

D72 · Other disorders of white blood cells

Excludes 2 · neutropenia (D70)

D72.81 · Decreased white blood cell count

Excludes 2 · neutropenia (D70)

R50.81 · Fever presenting with conditions classified elsewhere

Code first · neutropenia (D70.-)

sections/R70-R79 · Abnormal findings on examination of blood, without diagnosis (R70-R79)

Excludes 2 · abnormalities of white blood cells classified elsewhere (D70-D72)