Code edition

UpcomingOct 1, 2026 – Sep 30, 2027

D48.11UpcomingCategory · further specificity required

Desmoid tumor

D37-D48 · Inherited instructions

Excludes 1

neoplasms of unspecified behavior (D49.-)

D48 · Inherited instructions

Excludes 1

neurofibromatosis (nonmalignant) (Q85.0-)

D48.1 · Inherited instructions

Excludes 1

neoplasm of uncertain behavior of articular cartilage (D48.0)
neoplasm of uncertain behavior of cartilage of larynx (D38.0)
neoplasm of uncertain behavior of cartilage of nose (D38.5)
neoplasm of uncertain behavior of connective tissue of breast (D48.6-)

More specific codes

D48.110Desmoid tumor of head and neck D48.111Desmoid tumor of chest wall D48.112Desmoid tumor, intrathoracic D48.113Desmoid tumor of abdominal wall D48.114Desmoid tumor, intraabdominal D48.115Desmoid tumor of upper extremity and shoulder girdle D48.116Desmoid tumor of lower extremity and pelvic girdle D48.117Desmoid tumor of back D48.118Desmoid tumor of other site D48.119Desmoid tumor of unspecified site

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

First observed · 2023-10-01

Code history

Latest recorded change · FY2026

ChangedUnchanged

FY2026

Effective from 2025-10-01

Code-level rules changed

Desmoid tumor

Category — select a more specific code

CDC/NCHS · FY2026

All editions (7)

All editions	Effective from	Code history
FY2024	2023-10-01	Added
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	Code-level rules changed
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Inclusion terms

Aggressive fibromatosis

Inherited instructions

Chapters 2 · Neoplasms (C00-D49)

Note

Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

D37-D48 · Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

Excludes 1

neoplasms of unspecified behavior (D49.-)

Note

Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.

D48 · Neoplasm of uncertain behavior of other and unspecified sites

Excludes 1

neurofibromatosis (nonmalignant) (Q85.0-)

D48.1 · Neoplasm of uncertain behavior of connective and other soft tissue

Inclusion terms

Neoplasm of uncertain behavior of connective tissue of ear
Neoplasm of uncertain behavior of connective tissue of eyelid
Stromal tumors of uncertain behavior of digestive system

Excludes 1

neoplasm of uncertain behavior of articular cartilage (D48.0)
neoplasm of uncertain behavior of cartilage of larynx (D38.0)
neoplasm of uncertain behavior of cartilage of nose (D38.5)
neoplasm of uncertain behavior of connective tissue of breast (D48.6-)

More specific codes

Official index references (1)

Fibromatosis (1)

Fibromatosis › aggressiveDisease index

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
D48.19	Other specified neoplasm of uncertain behavior of connective and other soft tissue	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗