Z40.0CurrentCategory · further specificity required

Encounter for prophylactic surgery for risk factors related to malignant neoplasms

Code-level instructions

Use additional code

code to identify risk factor, such as genetic susceptibility to malignant neoplasm Z15.-

Z40 · Inherited instructions

Excludes 1

organ donations (Z52.-)
therapeutic organ removal-code to condition

Excludes 2 · 1

Z40-Z53 · Encounters for other specific health care (Z40-Z53)

Excludes 2

follow-up examination for medical surveillance after treatment (Z08-Z09)

More specific codes

Z40.00Encounter for prophylactic removal of unspecified organ Z40.01Encounter for prophylactic removal of breast Z40.02Encounter for prophylactic removal of ovary(s)Z40.03Encounter for prophylactic removal of fallopian tube(s)Z40.09Encounter for prophylactic removal of other organ

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

First observed · 2015-10-01

Code history

Latest recorded change · FY2026

ChangedUnchanged

FY2026

Effective from 2025-10-01

Code-level rules changed

Encounter for prophylactic surgery for risk factors related to malignant neoplasms

Category — select a more specific code

CDC/NCHS · FY2026

All editions (19)

All editions	Effective from	Code history
FY2016	2015-10-01	First observed
FY2017	2016-10-01	No tabular change
FY2018	2017-10-01	No tabular change
FY2019	2018-10-01	No tabular change
FY2020	2019-10-01	No tabular change
FY2020 · April	2020-04-01	No tabular change
FY2021	2020-10-01	No tabular change
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	Code-level rules changed
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Includes

Admission for prophylactic organ removal

Use additional code

code to identify risk factor, such as genetic susceptibility to malignant neoplasm Z15.-

Inherited instructions

Chapters 21 · Factors influencing health status and contact with health services (Z00-Z99)

Note

Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
(a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
(b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Z40-Z53 · Encounters for other specific health care (Z40-Z53)

Includes

Categories Z40-Z53 are intended for use to indicate a reason for care. They may be used for patients who have already been treated for a disease or injury, but who are receiving aftercare or prophylactic care, or care to consolidate the treatment, or to deal with a residual state

Excludes 2

follow-up examination for medical surveillance after treatment (Z08-Z09)

Z40 · Encounter for prophylactic surgery

Excludes 1

organ donations (Z52.-)
therapeutic organ removal-code to condition

More specific codes

Z40.00Encounter for prophylactic removal of unspecified organBillable / specific Z40.01Encounter for prophylactic removal of breastBillable / specific Z40.02Encounter for prophylactic removal of ovary(s)Billable / specific Z40.03Encounter for prophylactic removal of fallopian tube(s)Billable / specific Z40.09Encounter for prophylactic removal of other organBillable / specific

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
Z40.8	Encounter for other prophylactic surgery	Category · further specificity required
Z40.9	Encounter for prophylactic surgery, unspecified	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗

Z40.0CurrentCategory · further specificity required

Encounter for prophylactic surgery for risk factors related to malignant neoplasms

Code-level instructions

Use additional code

code to identify risk factor, such as genetic susceptibility to malignant neoplasm Z15.-

Z40 · Inherited instructions

Excludes 1

organ donations (Z52.-)
therapeutic organ removal-code to condition

Excludes 2 · 1

Z40-Z53 · Encounters for other specific health care (Z40-Z53)

Excludes 2

follow-up examination for medical surveillance after treatment (Z08-Z09)

More specific codes

Claims & coverage

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

First observed · 2015-10-01

Code history

Latest recorded change · FY2026

ChangedUnchanged

FY2026

Effective from 2025-10-01

Code-level rules changed

Encounter for prophylactic surgery for risk factors related to malignant neoplasms

Category — select a more specific code

CDC/NCHS · FY2026

All editions (19)

All editions	Effective from	Code history
FY2016	2015-10-01	First observed
FY2017	2016-10-01	No tabular change
FY2018	2017-10-01	No tabular change
FY2019	2018-10-01	No tabular change
FY2020	2019-10-01	No tabular change
FY2020 · April	2020-04-01	No tabular change
FY2021	2020-10-01	No tabular change
FY2021 · 01-01	2021-01-01	No tabular change
FY2022	2021-10-01	No tabular change
FY2022 · 04-01	2022-04-01	No tabular change
FY2023	2022-10-01	No tabular change
FY2023 · 04-01	2023-04-01	No tabular change
FY2024	2023-10-01	No tabular change
FY2024 · 04-01	2024-04-01	No tabular change
FY2025	2024-10-01	No tabular change
FY2025 · 04-01	2025-04-01	No tabular change
FY2026	2025-10-01	Code-level rules changed
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Includes

Admission for prophylactic organ removal

Use additional code

code to identify risk factor, such as genetic susceptibility to malignant neoplasm Z15.-

Inherited instructions

Chapters 21 · Factors influencing health status and contact with health services (Z00-Z99)

Note

Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
(a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
(b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Z40-Z53 · Encounters for other specific health care (Z40-Z53)

Includes

Excludes 2

follow-up examination for medical surveillance after treatment (Z08-Z09)

Z40 · Encounter for prophylactic surgery

Excludes 1

organ donations (Z52.-)
therapeutic organ removal-code to condition

More specific codes

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
Z40.8	Encounter for other prophylactic surgery	Category · further specificity required
Z40.9	Encounter for prophylactic surgery, unspecified	Billable / specific

Official titles and instructions are preserved in their source language. Official sources ↗