Code edition

CurrentApr 1, 2026 – Sep 30, 2026

Z15.3CurrentBillable / specificExempt from present-on-admission reporting

Genetic susceptibility to kidney disease

Code-level instructions

Code also

, if applicable, hypertension (I10-I1A)

Z15 · Inherited instructions

Use additional code

code, if applicable, for any associated family history of the disease (Z80-Z84)

Excludes 1

chromosomal anomalies (Q90-Q99)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Use the service date for outpatient/professional claims and the discharge date for hospital inpatient claims. Earlier encounters use ICD-9-CM; each individual code must also be valid for the applicable date.

Official coding guidelines → · CMS ↗

MS-DRG · 43.1 · 951

Grouping depends on the complete encounter and CMS grouper logic.

951 · Other Factors Influencing Health Status

2026-04-01 – 2026-09-30

CMS · MS-DRG 43.1

Check Medicare coverage ↗

First observed · 2025-10-01

Code history

Latest recorded change · FY2026

ChangedUnchanged

FY2026

Effective from 2025-10-01

Added

Genetic susceptibility to kidney disease

Billable diagnosis code

CDC/NCHS · FY2026

All editions (3)

All editions	Effective from	Code history
FY2026	2025-10-01	Added
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Code also

, if applicable, hypertension (I10-I1A)

Inherited instructions

Z15 · Genetic susceptibility to disease

Includes

confirmed abnormal gene

Excludes 1

chromosomal anomalies (Q90-Q99)

Use additional code

code, if applicable, for any associated family history of the disease (Z80-Z84)

Chapters 21 · Factors influencing health status and contact with health services (Z00-Z99)

Note

Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
(a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
(b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Official index references (1)

Genetic (1)

Genetic › susceptibility to disease NEC › kidney diseaseDisease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2025-10-01

Previous assignment: Z15.89

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
Z15.0	Genetic susceptibility to malignant neoplasm	Category · further specificity required
Z15.1	Genetic susceptibility to epilepsy and neurodevelopmental disorders	Billable / specific
Z15.2	Genetic susceptibility to obesity	Billable / specific
Z15.8	Genetic susceptibility to other disease	Category · further specificity required

Official titles and instructions are preserved in their source language. Official sources ↗

Z15.3CurrentBillable / specificExempt from present-on-admission reporting

Genetic susceptibility to kidney disease

Code-level instructions

Code also

, if applicable, hypertension (I10-I1A)

Z15 · Inherited instructions

Use additional code

code, if applicable, for any associated family history of the disease (Z80-Z84)

Excludes 1

chromosomal anomalies (Q90-Q99)

Claims & coverage

Coverage depends on the payer, service and applicable policy. A billable code does not guarantee payment.

When ICD-10-CM is required

For US diagnosis claims covered by HIPAA, ICD-10-CM is required from October 1, 2015.

Official coding guidelines → · CMS ↗

MS-DRG · 43.1 · 951

Grouping depends on the complete encounter and CMS grouper logic.

951 · Other Factors Influencing Health Status

2026-04-01 – 2026-09-30

CMS · MS-DRG 43.1

Check Medicare coverage ↗

First observed · 2025-10-01

Code history

Latest recorded change · FY2026

ChangedUnchanged

FY2026

Effective from 2025-10-01

Added

Genetic susceptibility to kidney disease

Billable diagnosis code

CDC/NCHS · FY2026

All editions (3)

All editions	Effective from	Code history
FY2026	2025-10-01	Added
FY2026 · April	2026-04-01	No tabular change
FY2027	2026-10-01	No tabular change

Code-level instructions

Code also

, if applicable, hypertension (I10-I1A)

Inherited instructions

Z15 · Genetic susceptibility to disease

Includes

confirmed abnormal gene

Excludes 1

chromosomal anomalies (Q90-Q99)

Use additional code

code, if applicable, for any associated family history of the disease (Z80-Z84)

Chapters 21 · Factors influencing health status and contact with health services (Z00-Z99)

Note

Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
(a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
(b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Official index references (1)

Genetic (1)

Genetic › susceptibility to disease NEC › kidney diseaseDisease index

Official conversion history

Historical assignments from the CDC conversion table support data retrieval. They do not authorize substituting a previous code for the current code.

Release dates 2025-10-01

Previous assignment: Z15.89

Related codes

Other entries in the same category; these are not automatic substitutes.

Code	Description	Category · further specificity required
Z15.0	Genetic susceptibility to malignant neoplasm	Category · further specificity required
Z15.1	Genetic susceptibility to epilepsy and neurodevelopmental disorders	Billable / specific
Z15.2	Genetic susceptibility to obesity	Billable / specific
Z15.8	Genetic susceptibility to other disease	Category · further specificity required

Official titles and instructions are preserved in their source language. Official sources ↗